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GI & Heart Disease

Improve cholesterol and blood pressure levels.

Supporting scientific papers:heart200


Low-Glycemic-Index Foods Can Decrease Systolic and Diastolic Blood Pressure in the Short Term.

This study investigated the effect of either a low GI or high GI diet on 30 women on two separate days and measured 24-hour blood pressure on each occasion. Both systolic (-10.6 mmHg) and diastolic (-7.5 mmHg) blood pressure decreased significantly on the low GI diet day, but did not change significantly on the high GI day. Hosseininasab et al. Int J Hypertens. Epub 2015 Oct 5


Low glycaemic index diets and blood lipids: a systematic review and meta-analysis of randomised controlled trials.

Low glycemic index diets are beneficial in the management of hyperglycemia. Cardiovascular diseases are the major cause of mortality in diabetes therefore it is important to understand the effects of GI on blood lipids. This meta-analysis provides consistent evidence that low GI diets reduce total and LDL-cholesterol and have no effect on HDL-cholesterol or triglycerides. Goff et al. Nutr Metab Cardiovasc Dis. 2013 Jan;23(1):1-10


Preliminary report: the effect of a 6-month dietary glycemic index manipulation in addition to healthy eating advice and weight loss on arterial compliance and 24-hour ambulatory blood pressure in men: a pilot study.

The authors aimed to determine whether altering dietary glycemic index in addition to healthy eating and weight loss advice affected arterial compliance and 24-hour blood pressure, both coronary heart disease risk factors. The results suggest that a Low GI diet may be beneficial in reducing CHD risk, even in the setting of healthy eating and weight loss. Philippou et al. Metabolism. 2009; 58(12):1703-8.


Decrease the risk of cardiovascular disease.

Supporting scientific papers:


Food consumption and the actual statistics of cardiovascular diseases: an epidemiological comparison of 42 European countries. 

The aim of this ecological study was to identify the main nutritional factors related to the prevalence of cardiovascular diseases (CVDs) in Europe, based on a comparison of international statistics.The results showed that there is no association between CVDs and saturated fat, which is still contained in official dietary guidelines. Instead, they agree with data accumulated from recent studies that link CVD risk with the high glycaemic index/load of carbohydrate-based diets. Food & Nutrition Research 2016, 60: 31694 – http://dx.doi.org/10.3402/fnr.v60.31694.


Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: the diet, obesity, and genes (DiOGenes) study: a randomized, controlled trial.

This study found that low glycemic index carbohydrates and, to a lesser extent, low protein intake may specifically reduce low-grade inflammation and associated comorbidities in overweight/obese adults. Gögebakan et al. Circulation. 2011 Dec 20;124(25):2829-38.


Associations of Glycemic Index and Load with Coronary Heart Disease Events: A Systematic Review and Meta-Analysis of Prospective Cohorts.

This review established that high GI and GL diets were significantly positively associated with CHD events in women but not in men. Further studies are required to determine the relationship between GI and GL with CHD in men. Mirrahimi, A et al.J Am Heart Assoc. October 12, 2012


Glycemic load, glycemic index and risk of cardiovascular diseases: meta-analyses of prospective studies.

It was found that high GL and GI diets were associated with significant increased risk of cardiovascular disease, specifically for women. Ma XY, et al. Atherosclerosis; 2012 Aug;223(2):491-6


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